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Three-parent IVF may be made legal

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Three-parent IVF may be made legalPA


The Department of Health has asked the fertility regulator to conduct a public consultation into the acceptability of a controversial technique known as 'three-parent IVF'.

The technique, which involves using genetic material from three parents - two women and a man - to create a baby, is currently banned in the UK.

However the procedure could help the estimated 12,000 people who have mitochondrial disease - defects in the structures called mitochondria which surround the cell nucleus.

The inherited disease is passed down the maternal line. About 100 babies are born each year with a severe form of the incurable disease, with many dying in infancy.

The technique involves taking healthy DNA from a mother's egg, either before or after fertilisation - and transferring it into an egg donated by another woman.

This egg is than implanted into the mother to avoid passing on defects in her mitochondria.

Although the child would then have genetic material from its mother, father and the donor, it would not inherit any of the donor's characteristics.

The Daily Mail reports that the procedure has caused an ethical storm, with critics warning that these 'hybrid' children could pose unknown risks for future generations.

Mitochondria are sausage-shaped 'batteries' which float around inside cells converting food into energy that the body can use. Each contains a tiny strand of DNA - around 37 of the 23,000 human genes, which is passed on by the mother.

Mutations in this DNA can cause around 50 serious and untreatable genetic diseases which affect around one in 5,000 children, causing symptoms such as blindness, deafness, heart and kidney problems and early-onset dementia. Many sufferers die before reaching adulthood.

If the mother's damaged mitochondria could be cut out of the fertilisation process, it is hoped that these diseases could be prevented, saving 100 lives a year.

The Independent reports that Public Health Minister Anne Milton said: "Mitochondrial disease... can have a devastating impact on the people who inherit it. Scientists have developed a new procedure to stop these diseases being passed on. But such a procedure would not be allowed... under current laws, so we are consulting the public as to whether we should change the law."

Professor Doug Turnbull, who will be the director of the University of Newcastle's new research centre for mitochondrial disease, said: "If this technology proves to be as safe as IVF and as effective as preliminary studies show, I think we could totally prevent transmission of these diseases."

However, the procedure is not without critics. The Society for the Protection of Unborn Children told The Independent: "These macabre experiments are both destructive and dangerous and therefore unethical. Scientists should abandon the spurious field of destructive embryo experimentation and instead promote the ethical alternative of adult stem-cell research, which is already providing cures and treatments for the same conditions."

The public consultation by the Human Fertilisation and Embryology Authority will start later this year.

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Could a daily dose of statins beat cancer?

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Could a daily dose of statins beat cancer?AFP/Getty


Experts believe that cholesterol-busting pills called statins could help to beat cancer.

The drug, which is taken by millions to lower cholesterol and reduce the risk of heart attack and stroke, has also been shown to block the growth and spread of tumours.

Costing as little as 40p per day, the findings are believed to have "great implications" in the battle to beat cancer.

The study, which was carried out on breast cancer, was conducted at Columbia University in New York.

Dr Carol Prives, who led the study, looked at the mutation of a gene called p53 that suppresses tumours.

The Daily Express reports that mutations in this gene have been identified as the most frequent abnormality detected in cancer, and scientists believe that understanding how it works could provide valuable information for treating or preventing the disease.

Researchers found a link between a cholesterol-building mechanism in the body and the disorganised cell growth which is characteristic of breast cancer. Both involved defective versions of p53.

More than half of human cancers carry mutations in the gene and many of these give p53 new functions that fuel the formation of cancer.

By studying cancer cells grown in an artificial system that resembles the human breast, researchers discovered that cells carrying mutant p53 grow in an invasive manor, just like breast cancer.

When levels of the mutant gene were lowered, cells grew more normally. When cells which contained mutant p53 were treated with statins they stopped their invasive growth and, in some cases, died.

Dr Prives said: "The data raises the possibility that we might identify patients whose tumours may respond to statins. Of course we can't make any definitive conclusions until we know more. There are great implications. Perhaps one could do a clinical trial, and that may support these findings, or it may be more complicated."

Dr Caitlin Palframan of Breakthrough Breast Cancer, said: "We are exited that existing drugs, like statins, are showing potential in the fight against breast cancer. This research identifies a relatively large group of breast cancer patients who could be targeted with statins, though we will need to see the results of clinical trials to know whether this will work."

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Scientists fail to find the G-Spot

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Scientists fail to find the G-SpotGetty


Some men have been looking for the G-Spot for years, but now scientists say that it might not exist after all.

After reviewing 100 studies conducted over the last 60 years, researchers at the Yale-New Haven Hospital in Connecticut found no evidence to support its existence.

Research leader Dr Amichai Kilchevsky, a urologist, blames pornography, magazines and sex therapists for putting couples under too much pressure to locate the fabled epicentre of female sexual pleasure.

He wrote in the Journal of Sexual Medicine: "Objective measures have failed to provide strong and consistent evidence for the existence of an anatomical site that could be related to the famed G-Spot."

However he admits that "modern investigative techniques" might help to find it and said that it merits further study.

The Daily Mail reports that the G-Spot is said to be a small area inside the vagina which is packed with nerve endings and capable of providing intense pleasure when stimulated.

In 2010 a UK study also failed to prove its existence and concluded that the idea of it made couples feel inadequate about their sex lives.

Dr Kilchevsky said: "Lots of women feel almost as though it is their fault they can't find it. The reality is that it is probably not something, historically or evolutionarily, that should even exist."

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Scientists say that lack of sleep can be fatal

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Scientists say that lack of sleep can be fatalGetty


New research suggests that long-term sleep deprivation can be fatal - and it is rarely identified or treated by doctors.

The Daily Mail reports that at least 86 medical sleep disorders have been identified, all of which raise the risk of developing illnesses such as depression, diabetes and high blood pressure.

Consequently a review in Online First in The Lancet medical journal says that doctors should routinely ask patients about their sleeping habits as this may be at the root of other health problems.

The review says that around one in four adults in Britain have sleeping problems, with one in ten suffering from an insomnia disorder.

The authors, Charles Morin from the Université Laval, Québec City, Canada and Ruth Benca from the Univeristy of Wisconsin, Madison, USA said that insomnia has "substantial long-term effects" on people's physical and psychological health.

They said: "Despite advances in diagnosis and management insomnia is still under-recognised and often goes untreated.

"In view of the high prevalence and substantial morbidities of insomnia, patients should routinely be asked about sleep problems by health-care providers."

Research shows that people who sleep for between six and eight hours sleep per night are likely to live longer and enjoy better health. People who sleep for less than six hours are at more risk of premature death.

Figures suggest that around one third of UK adults regularly sleep for less than five hours per night, with the average being seven hours.

People with insomnia are five times more likely to suffer from anxiety and depression and are twice as likely to develop congestive heart failure and diabetes.

The review says that doctors should be more willing to treat insomniacs with cognitive behavioural therapy and drugs that haven't been approved for combating sleeping problems, such as antidepressants and antihistamines.

Sleep expert Dr Neil Stanley, who is the ex-Chairman of the British Sleep Society, said that insomnia is "completely neglected by doctors the NHS and the Government.

He says: "Government policy makers always have something to say about diet and exercise, why don't they get into the bedroom and tell people about the value of sleep."

He adds: "We urgently need to pay more attention to sleep with clear advice to children in schools, parents and throughout adult life."

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Cake and Eat It: Banana fritters with sesame caramel

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Cake and Eat It: Banana fritters with sesame caramelJassy Davis

This week's recipe features soft, squidgy chunks of banana deep-fried in crunchy batter and served with a golden swirl of sesame caramel. It's not a pudding you'll find offered much in China, but it's a staple of the Anglo-Cantonese take-aways that opened up across the UK in the 1950s and 1960s.

These take-away restaurants were set up by immigrants who were mostly from Hong Kong. They simplified the Cantonese dishes of their homeland and adapted them to suit our notoriously sweet palate. As well as sweetening and saucing up their recipes, the take-away owners also needed to adapt their cuisine to fit the 'starter, main and pudding' pattern of British dining.

Dessert isn't a regular part of a meal in China, but a bit of creativity meant British diners could finish their Chinese banquet with banana or pineapple fritters, often dipped in syrup to give them a crisp, glossy finish. So, while they may not be authentically Chinese, banana fritters are a well-loved part of eating out in Britain.

And why not? The combination of hot, crunchy batter giving way to sweet banana is delicious - especially with a scoop of slowly melting vanilla ice cream.

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Warm fritters, hot caramel and a scoop of ice-cold ice cream make the perfect end to a Chinese New Year feast

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These fritters are actually very quick to make at home. If you have a deep-fat fryer, heat it to 180°C/350°F to cook the fritters. If you're heating oil in a saucepan (which I did), be careful with it. You can use a thermometer to check when the oil has reached the right temperature, or use the old-fashioned trick of dropping a cube of white bread in to see if it browns and sizzles.


Don't leave the pan untended while you're cooking, don't drop anything into the oil (being splashed with hot oil is no fun), don't let water get near it, and as soon as you've finished cooking, remove the oil from the heat and leave it somewhere safe to cool down.

These fritters are best eaten as soon after cooking as possible. Keep them warm in a low oven while you quickly make the caramel - it's easy to burn, so keep your eyes fixed on the pan while the sugar browns. The warm fritters, hot caramel and a scoop of ice-cold ice cream make the perfect end to a Chinese New Year feast. Gung Hei Fat Choi!

Banana fritters with sesame caramel

5 minutes to prepare, 15 minutes to cook
Serves 4
Cook's note: Suitable for vegetarians

150g plain flour
1 tsp baking powder
225ml sparkling water
4 bananas, peeled and sliced into 5-6 chunks each
Sunflower oil, for deep-fat frying
50g caster sugar
1 tbsp sesame seeds
Vanilla ice cream, to serve

Sift the flour and baking powder into a mixing bowl, then whisk in the sparkling water to make a smooth batter. Stir in the bananas to completely coat them.

Pour enough sunflower oil into a medium-sized pan to half fill it and heat until a small chunk of bread dropped into it sizzles and begins to brown.

Carefully lower in 4-5 chunks of banana (don't crowd the pan) and deep-fry for 1-2 minutes, until golden brown. Lift out of the fat with a heatproof slotted spoon and drain on kitchen towel. Repeat with the remaining bananas until they are all cooked. Keep warm in a low oven.

Place the caster sugar, sesame seeds and 50ml cold water in a deep, heavy-based frying pan and heat, swirling the pan occasionally but not stirring the sugar, over a medium heat until the sugar has dissolved. Turn up the heat and cook for 1-2 minutes, swirling the pan frequently, or until the caramel is golden. Immediately remove from the heat.

Divide the banana fritters between 4 warm plates and serve with a scoop of vanilla ice cream and a drizzle of the sesame caramel sauce.

 

Private abortion clinics to be allowed to advertise on TV

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Private abortion clinics to be allowed to advertise on TVPA


Advertising watchdogs ruled yesterday that private clinics that carry out abortions for profit will be allowed to promote their services on TV and radio.

Until now, restrictions have meant that only not-for-profit organisations have been allowed to advertise family planning services, including abortion.

This is why just one advert, by charity Marie Stopes International, has ever been aired on TV. The Daily Mail reports that when it was shown in 2010 it attracted more than 4,500 complaints.

There are more than 35 private hospitals in England that offer abortion services, with many also offering maternity and fertility services. However it is not known how many of these will choose to advertise or whether the adverts will be screened before the watershed.

The Telegraph reports that the two bodies responsible for Britain's advertising codes, The Committee of Advertising Practice (CAP) and the Broadcast Committee of Advertising Practice (BCAP), said it had become impossible to justify not allowing companies to advertise because the services they offer are legal.

Campaigners have warned that this could lead to a flood of advertising that risks trivialising abortion.

Mark Bhagwandin, from the pro-life charity Life, said: "This is an extremely disappointing decision.

"The abortion industry has a lot of money behind it and these companies will have the means to run prime time television and radio advertising campaigns.

"This will trivialise and commercialise the decision to terminate a baby, putting it on the same footing as choosing other products advertised on television.

"I have no doubt that we will see a rise in abortions as a result of this."

Matt Wilson, a spokesman for BCAP, said: "There is not going to be some sort of free-for-all saying 'come to us to get an abortion'.

"They are not there to promote abortion, they have to promote an array of services. It is about being responsible and commercial pro-lie pregnancy services will now be able to advertise too."

Do you think that TV adverts will influence a woman's decision to have a termination? Let us know below...

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Flowers really do put women in the mood for love

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Flowers really do put women in the mood for lovePA


A new study has found that a woman is more likely to find a man attractive and accept a date with a stranger if she is near some flowers.

Scientists say that the man doesn't even need to have bought the flowers himself - as long as there are some nearby, women are more inclined to be receptive to his advances.

The research was conducted by Dr Nicolas Gueguen, a psychologist a the University of South Brittany, who studies the science of attraction.

The Daily Mail reports that he asked 46 female student volunteers to sit a room on their own and watch a video of a man talking about himself.

Half the students watched the video in a room that contained three vases of flowers, a mix of roses, daisies and marigolds. The rest sat in an identical room without flowers.

He found that the women who watched in the room decorated with flowers rated the man as more attractive and were more willing to go on a date with him.

In a second study, the same experiment was repeated with 122 single women aged from 18 to 20.

This time, after watching the video, they were led into a room where the man was waiting. They were old he was a fellow student taking part in the experiment, but he was really an actor, recruited by the scientists.

When they were left alone, the man was instructed to talk for five minutes about the experiment and then ask the woman on a date. Each time he used the same words.

Again, the presence of flowers made the women more receptive. Half of those who watched the video in a the room without flowers accepted the offer of the date, but that rose to 81 per cent for those who had been close to the blooms.

Dr Gueguen said: "These results confirm the popular conception that flowers are able to activate romance and act as a facilitator in dating."

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Long-lasting celebrity marriages

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Long-lasting celebrity marriagesEMPICS Entertainment; AFP/Getty Images

Not all celebrity marriages crash and burn in a short matter of weeks or months. Some celebrity couples - despite their years in the spotlight - are still going strong from one decade to the next.

Take a look at some of our favourite long-lasting celebrity marriages and uncover the marriage secrets of the stars that keep them living happily ever after.

 


Anti-miscarriage drug could cause cancer in daughters of women who took it decades ago

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Anti-miscarriage drug could cause cancer in daughters of women who took it decades agoPA


Tens of thousands of British women whose mothers were prescribed a common pregnancy drug called DES are now at risk of cancer, say experts.

The drug, called diethylstilboestrol, was widely prescribed between 1938 and 1971 because doctors wrongly believed that it could reduce the risk of miscarriage.

In 1971 the US Food and Drug Administration told doctors to stop prescribing DES when it discovered that one in 1,000 daughters of women who had taken it developed a rare form of vaginal and cervical cancer called clear cell adenocarcinoma (CCAC). UK doctors were advised against prescribing it in 1973.

Recent studies have also linked it to an increased risk of breast cancer and fertility problems.

A report in The Independent on Sunday reveals that there is even concern that the drug, known as the 'silent Thalidomide', could affect third generations - the granddaughters of the women who originally took it.

The Daily Mail reports that around 2,000 women have already brought cases against drug companies in America, with around $1.5billion paid out in compensation so far.

No cases have yet been brought in Britain but Washington-based lawyer Aaron Levine is travelling to the UK in two weeks to search for the 'DES daughters' who have been unable to claim compensation in British courts.

Mr Levine says: "It never worked. it was like leeches or bleeding or copper rings. It didn't do anything positive for anyone, and didn't help anyone's pregnancy. What is striking is that it was banned in 1971 here [in the US], but that it continued to be sold years later in the UK."

The Royal College of Obstetrics and Gynaecology estimates that 7,000 women in the UK were given the drug and 3,500 exposed girls were born between 1940 and 1971. Other reports estimate that up to 300,000 people in Britain were exposed.

All DES daughters carry a lifelong risk of CCAC and are 40 times more likely to develop it than women who have not been exposed to the drug. Most cases have occurred in women in their late teens and early twenties, and it is estimated that at least 25 per cent of those diagnosed died from their illness.

A recent US study suggests that breast cancer risk is almost doubled in DES daughters over the age of 40, with women having a one-in-25 chance of developing the disease by 55.

Other studies have found an increased risk of premature birth, miscarriage and ectopic pregnancy and 'DES sons' may have a higher risk of undescended testes, cysts on the testes and lowered sperm count.

A Department of Health spokesperson told The Independent on Sunday that the issue was "complex" and said they have "every sympathy" for those affected. She added: "With regard to compensation for people who believe they have been adversely affected by this drug, this is a matter for the manufacturer(s) and/or the UK licensees of the drug."

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Women warned not to have weight-loss operations overseas

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Women warned not to have weight-loss operations overseasPA


Leading surgeons have warned British women not to travel overseas for cut-price weight-loss surgery due to the high risk of complications.

It seems that thousands of British women are now travelling to private clinics abroad because they are unable to get surgery on the NHS or have to spend an average of 18 months on a waiting list.

The Independent on Sunday reports that in countries such as Syria gastric bands are being fitted for as little as £2,000, compared to £6,500 in the UK.

Last year a report warned that women may develop complications years after having the surgery and Ahmed R Ahmed, a weight loss surgeon at the Cromwell Hospital in London, believes that as many as 10 per cent of women who have surgery overseas are returning with complications.

He says: "It appears that some patients who pay privately abroad are not getting high-quality surgery and certainly they're not getting any follow-up.

"The key thing is the follow-up. If you don't have that, patients can get malnourished and deficient in vitamins. There is also a strong chance their weight might not go down as much as it should."

Catherine Foss, executive director of the International Society of Aesthetic Plastic Surgery, says: "We see travel agencies brokering surgery for their clients with surgeons they have never met. The patients have no assurance that their surgeon is properly trained or qualified to perform the procedure they will undergo."

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Could flavonoids in fruit and veg stop cancer in its tracks?

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Could flavonoids in fruit and veg stop cancer in its tracks?PA

Scientists have found a compound contained in many fruits and vegetables could play a key role in inhibiting the growth of cancer cells.

The South Korean study discovered that the plant flavonoid luteolin can interfere with the communication process cancer cells rely on to spread.

The researchers, whose work was published in BMC Gastroenterology, said luteolin, which is found in green peppers, carrots, olive oil, rosemary, peppermint, oranges and celery, could stop the growth of colon cancer cells.

The team said the flavonoid appeared to stop cancer cells secreting a 'pathway receptor' which they need in order to spread.

Team leader Professor Jung Han Yoon Park said: "Blocking these pathways stops cancer cells from dividing and leads to cell death."

"Our study, showing that luteolin interferes with cell signalling in colon cancer cells, is a step forward in understanding how this flavonoid works."

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Experts call for cosmetic surgery advertising ban

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Experts call for cosmetic surgery advertising banGetty

Plastic surgery experts have said adverts which promote cosmetic surgery should be banned.

The British Association of Aesthetic Plastic Surgeons (BAAPS) called for surgeons to undergo annual checks as part of a range of measures to address issues in the industry.

Last week, Professor Sir Bruce Keogh - the head of a government review into the plastic surgery industry - said patients could be asked to take out insurance to cover them in the case of problems.

BAAPS experts said advertising cosmetic surgery should not be allowed, as it was a medical procedure.

They also said all silicone implants should be registered, to avoid the same problems as the recent PiP implant scandal, where implants were filled with industrial grade silicone.

The experts also want dermal fillers, used to boost lips, enhance cheekbones and fill wrinkles, to be subject to tighter regulations.

BAAPS president Fazel Fatah said "it is an absolute joy for us at the BAAPS to hear that this year, the Government will be examining the lax regulations in our sector."

He added: "Over the last decade the BAAPS has worked tirelessly to educate the public on the many aggressive marketing gimmicks that not only trivialise surgery but endanger the patient."

"We have warned against the unrealistic expectations set by reality 'makeover' shows and against crass competition prizes promising 'mummy makeovers' and body overhauls."

"In no other area of surgery would one encounter Christmas vouchers and two-for-one offers - the pendulum has swung too far, and it is time for change. Thus we are delighted with the upcoming inquiry and put forward our realistic and achievable proposals for consideration by the Government."

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Meet the 32 stone mother-of-three Sumo wrestling champion

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Meet the 32 stone mother-of-three Sumo wrestling championBarcroft

Sharran Alexander is the latest heavyweight British sporting superstar.

The mum-of-three from west London has scooped up four gold medals for Britain in international sumo wrestling competitions.

Sharran, who weighs 32 stone, was delighted to find that the Japanese form of wrestling was appropriate for her six foot height and weight.

She explained to the Sun: "There's not many sports women my size can do, so when I found sumo six years ago it changed my life."

"I used to be ashamed of my size and wore unflattering clothes - but after taking up sumo up I learned to love my body."

The 46-year-old says she got ready for fights by eating 5,000 calories a day, including Crunchy Nut cornflakes, pasta, chicken and huge bowls of rice.

She aded: "I used to train with the British women's team in Derby, but it no longer exists. I am the team!"

Sharran is getting ready for training with the Japanese female sumo wrestling team later in January.

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Home electricals: 50%+ discount deals

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On the hunt for the last of the January clearance bargains? Whether you're after a low-cost kettle or cut-price food processor, there are still some great deals to be had.

So, we've put together a selection of the best home electricals, all discounted by a whopping 50% or more. Take the sweat out of sales shopping and save a fortune with these thrifty finds.

Home electricals: 50%+ discount dealsAmazon/Sainsbury's

Half price until February 8th, this powerful handheld vacuum cleaner is just what you need to spring clean your car or deal with pesky crumbs down the sofa. It boasts an alligator-style mouth for easy cleaning and a retractable crevice tool to get into those hard-to-reach corners.

Get your Vax H90-GA-B Gator Orange Handheld Vacuum today for just £38.94 from Sainsbury's

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Home electricals: 50%+ discount dealsSainsbury's

Save an impressive 50% on this family-sized heath grill by George Foreman. Energy-efficient and time-saving, its unique design ensures excess fat is channelled away for crispy, grease-free results.

Snap up the George Foreman Silver Family Grill now, on sale at just £29.99 from Amazon

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Home electricals: 50%+ discount dealsAmazon

Pocket a generous 60% saving on this super-stylish white Prestige kettle. It wows with a powerful 3000W element, a generous 1.5 litre capacity and it swivels at the base for ease of movement.

Bag the bargain Prestige White Kettle today for just £19.99 from Sainsbury's

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Home electricals: 50%+ discount dealsSainsbury's

Nail your healthy eating plan with this handy steamer. Reduced by half, it boasts a hefty nine litre capacity, a simple-to-use rice bowl and a price tag that's as lean as you'll hopefully be.

Buy the Russell Hobbs 15071 Food Steamer today for only £22.49 Amazon

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Home electricals: 50%+ discount dealsAmazon

Save 60% on this swish stainless steel four-slice toaster. Features include extra wide slots for buns and bagels, a handy re-heat function and an easy-to-clean crumb tray.

Get your Breville Brushed Stainless Steel Toaster today for just £28.94 from Sainsbury's

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Home electricals: 50%+ discount dealsSainsbury's

Now half price, this top-rated food processor is a super-compact kitchen must-have. A great multi-tasker, it comes with five different accessories that perform 15+ functions, from kneading to shredding.

Snap up the Philips HR7620/70 Daily Collection Food Processor for only £30 from Amazon

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Home electricals: 50%+ discount dealsAmazon

Save 57% on this Morphy Richards Turbosteam iron in eye-catching purple. It rocks tip technology, with a ceramic soleplate and a potent shot of steam to glide effortlessly over your garments and tackle the most stubborn creases.

Get your Morphy Richards Turbosteam 40698 now for just £25.94 from Amazon

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Home electricals: 50%+ discount dealsAmazon

A useful addition to your kitchen, this Breville hand blender is reduced by a huge 60%. Perfect for blitzing soups and making smoothies, it features an ergonomic design and two speed options.

Bag the Breville VHB096 Hand Blender today for just £15.94 from Sainsbury's

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Home electricals: 50%+ discount dealsSainsbury's

 

Bargain tech: 50%+ discount deals

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The January sales are almost done and dusted, but there are still some great tech bargains out there.

So, to save you the hassle of hunting, we've rounded-up a selection of the best. Whether you're after a budget Blu-ray player or a low-cost laptop, save your pennies with these wallet-friendly finds.

Bargain tech: 50%+ discount dealsLenovo/Amazon

Save a fantastic 50% on this Red iPhone Step Up speaker. Superb value-for-money, it boasts decent sound quality for the price bracket, and includes a handy headphone socket.

Snap up the Red iPhone Step Up Speaker today for just £29.99 from Sainsbury's

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Bargain tech: 50%+ discount dealsSainsbury's

Pocket a generous 56% discount on this Epson Stylus all-in-one printer. It features a compact, space-saving design, PC-free printing and four individual ink sockets to save you even more money.

Bag your Epson Stylus SX435W All-in-One Inkjet Printer now for just £44.99 from Laskys

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Bargain tech: 50%+ discount dealsLaskys

Reduced by a hefty 60%, these noise cancelling headphones by Goldring rock an impressive frequency response and Goldring ANR (Active Noise Reduction) technology.

Get your Goldring NS1000 Noise Cancelling Headphones now for only £59.99 from Superfi

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Bargain tech: 50%+ discount dealsSuperfi

Save 53% on this top-rated Sony micro system. It comprises a CD player, iPod dock, DAD/FM tuner and superior 10W RMS output sound quality. And all for well under £100!

Snap up the Sony CMT-FX350i Micro Hi-Fi System now for just £88.19 from Amazon

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Bargain tech: 50%+ discount dealsAmazon

The price of this 3D-capable Blu-ray player has been slashed by a massive 54%. The player includes Smart TV Access so you stream thousands of movies, shows and online videos direct to your TV from your wireless internet connection.

Buy the LG BD550 Blu-ray Disc Player today for only £64.99 from Sainsbury's

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Bargain tech: 50%+ discount dealsSainsbury's

Impressing with a solid build, 250 name and number Directory, and an integrated digital answer machine, this BT Synergy phone is reduced by an equally impressive 51%.

Invest in the BT Synergy 5500 DECT Quad Cordless Phone now for just £59.99 Amazon

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One-Pot Winter Warmers: Roasted mushrooms with garlic butter, anchovies and crispy crumbs

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One-Pot Winter Warmers: Roasted mushrooms with garlic butter, anchovies and crispy crumbsHelen Graves

This week's one-pot recipe is very simple, yet packed with flavours: button mushrooms are roasted in garlic butter, latticed with anchovies and crowned with a crispy crumb topping.

There are few flavour combinations more harmonious than mushrooms, garlic and butter. The smell of the three cooking together is just incredible, akin to the smell of sizzling bacon in its power to draw people to the kitchen like moths to a flame.

The poor button mushroom doesn't get much of a look in these days, the reason being that it lacks the complexity of flavour that other, fancier mushrooms boast. The button shroom is perfect for slathering in garlic butter however, as it soaks up the golden juices like a fat, hungry sponge and, while still tasting mushroom-y, won't clash or fight for attention.

As I said, this couldn't be simpler. Once mushrooms are layered in a baking dish, they're strewn with anchovies and splodged with garlic butter, which sizzles and melts, taking the anchovies with it. A sprinkle of breadcrumbs during the last ten minutes of cooking provides a nice crunch on top.

If you're not into anchovies, they could of course be omitted but I urge you to try just a few; they will melt their savouriness into the sauce, while abandoning any previous fishiness.

Once the mushrooms are cooked, they just need a simple sprinkle of lemon juice and chopped parsley. Serve them with hunks of crusty bread for soaking up the puddles of garlic butter at the bottom.


Roasted mushrooms with garlic butter, anchovies and crispy crumbs (serves 4 as a starter or side dish; 2 as a vampire-busting lunch)

600g button mushrooms
3 large cloves garlic, crushed
100g butter, at room temperature
1 x 50g tin anchovies in oil, drained
A large handful of white breadcrumbs
Small handful parsley leaves, finely chopped
1 lemon
Black pepper

Bread, to serve

Preheat the oven to 200C. Give the mushrooms a wipe to remove any dirt and add them to a roasting tray in which they will sit in several layers (mine was 23 x 23cm). Lay the anchovy fillets evenly over the top of the mushrooms.

Mash the garlic together with the butter and dot it evenly(ish) over the mushrooms, then season well with black pepper. Cook for 15 minutes, then remove from the oven, stir well and scatter over the crumbs. Return to the oven and cook for a further 10 minutes.

When cooked, squeeze over the juice of half a lemon (you may want more later on) and scatter over the parsley. Serve with wedges of bread.

 

Why men are to blame for the world's problems

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Why men are to blame for the world's problemsGetty

Wars, financial meltdown, dictators - which sex dominates when it comes to causing trouble?

Researchers have investigated why men seem so intent on stirring up problems wherever they go, as part of a study published in the Philosophical Transactions of the Royal Society B.

They found men are more likely to fight in order to resolve a conflict of interest, while women will seek a peaceful solution and are more likely to "tend and befriend".

Professor Mark van Vugt, of Oxford University's Institute of Cognitive and Evolutionary Anthropology, said: "A solution to conflict  [is still] elusive. One reason might be the difficulty we have in changing our mindset, which has evolved over thousands of years."

The researchers said tribal men tended to gather in groups and fight against each other, which helped them to attract, defend and keep females interested.

"We see similar behaviour in chimpanzees," said Prof van Vugt. "For example, the males continuously monitor the borders of their territory."

"If a female from another group comes along, she may be persuaded to emigrate to his group. When a male strays too far, however, he is likely to be brutally beaten and possibly killed."

Are men more likely to cause trouble than women or have the researchers got it wrong? Let us know below...


And click through the gallery below to see if you're in need of an intimacy boost.


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Increase in patients dying from dehydration or malnutrition in Britain

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Increase in patients dying from dehydration or malnutrition in BritainCorbis

Figures have revealed a rise in the number of patients in hospitals dying from dehydration and malnutrition.

The new data showed four patients a day died from hunger or thirst in NHS and private hospitals in England.

The information, published by the Office for National Statistics, showed that in 2010 48 patients' deaths were caused by malnutrition, while 155 were caused by dehydration.

An additional 812 patients were found to be suffering from dehydration when they died, along with 301 who were malnourished, although this was not the cause of death.

Ten years ago, figures showed that 862 deaths were associated with the two conditions, while in 2010 the number had increased to 1,316.

A Department of Health spokesman said: "Many patients who suffer or die from malnutrition and dehydration are admitted to hospital with these conditions and have underlying health conditions like cancer that make them more susceptible to these problems."

"However, every NHS patient has the right to expect that they are looked after properly in hospital."

However Katherine Murphy, chief executive of the Patients Association, told the Daily Mail: "These figures are a terrible indictment of our precious National Health Service. They represent avoidable deaths. These people needed our care when they were at their most vulnerable."

Michelle Mitchell, charity director at Age UK, said: "There must be systematic monitoring of malnutrition in older patients. From the hospital ward to the hospital board, everyone needs to take responsibility and help stop this scandal."

Are patients dying of hunger and thirst? Let us know below...

And don't miss our gallery of immune-boosting tips...



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Mum banned from nightclubs for being "too old" to wear revealing outfits

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Mum banned from nightclubs for being 'too old' to wear revealing outfitsSWNS

Lisa Woodman is proud of her size 6, 34DD figure.

However she said she was "shocked and humiliated" to be turned away and given a life ban from three clubs in Worcester in the West Midlands.

One doorman told her she was "too old" to be wearing revealing outfits, although she is only 28.

The mum-of-four said she burst into tears on New Year's Eve when the doorman at Mode nightclub told her "You're too old to wear that get-up."

Lisa has also been refused entry at two other clubs in Worcester, Tramps and Velvet, which are managed by the same company.

Mum banned from nightclubs for being 'too old' to wear revealing outfitsSWNS

Lisa said "One doorman even made me walk up and down and turn around in front of people laughing at what I was wearing."

"I was totally in shock and really humiliated. I look after myself and I'm only 28. I just want to be treated with a bit of respect."

She added: "None of the pubs give me any hassle about my outfits so why do the nightclubs have such a problem? There were teenagers and girls in their 20s wearing much more revealing outfits but they went straight in."

"I rang the nightclub to complain but they just don't listen. The door staff told me I was banned for life unless I dress differently. It's outrageous."

"I always like to look sexy when I go out on the town,' she explained. "I split up from my partner last year and I was really upset so I had a boob job in April and got into shape going to the gym and now I just want to flaunt what I've got."

"I normally wear short skirts and one-piece outfits which might be revealing but never show off too much. I like my high-heel boots and mini-skirts. I've got loads of them - they usually cost between £20 and £50 but when I let my hair down, I like to look my best."

Dean Hill, director of Nexum Leisure, which runs the clubs, said: "We expect people to make an effort and we have a dress code of smart casual. It is the venue managers who are on the doors - they make decisions on the doors based on our policies."

Should Lisa be able to wear what she likes or were the clubs right to turn her away? Let us know below...

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Could puzzles prevent Alzheimer's disease?

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Could puzzles prevent Alzheimer's disease?Getty

If you're a fan of crossword puzzles, word games or Sudoku, you could be doing your brain a favour.

Researchers from the University of California said game-playing helped to keep the brain from developing a type of plaque associated with Alzheimer's disease.

Around 700,000 people in Britain suffer from Alzheimer's disease, with the number expected to double by 2030.

The study, published in the Archives of Neurology, looked at the levels of a protein called beta-amyloid plaque in 65 healthy patients who were all 76 years old.

Beta-amyloid protein damages the brain by attaching itself to nerve cells, which prevent the cells communicating properly, causing memory problems and personality changes.

The team compared levels of the protein in the healthy older patients with those of ten 75-year-olds with Alzheimer's and 11 who were 25 years old and in good health.

They said smaller amounts of the protein were found on the brains of people who enjoyed playing games, reading and writing.

Lead researcher Susan Landau said: 'We report a direct association, suggesting that lifestyle factors found in individuals with high cognitive engagement may prevent or slow deposition of beta amyloid, perhaps influencing the onset and progression of Alzheimer's disease."

She added: "Cognitive activity is just one component of a complex set of lifestyle practices linked to Alzheimer's disease risk. However, the present findings extend previous findings that link cognitive stimulation and Alzheimer's disease risk."

Dr Anne Corbett from the Alzheimer's Society said the study was "interesting" but "small", and further research needed to be carried out.

She commented: "It is too early to say whether keeping your brain active can reduce your risk of developing dementia, or how this might work. However, we would encourage anyone who enjoys cognitively stimulating activities such as reading, writing and playing games to keep it up."

Do you think keeping your brain active can prevent Alzheimer's or not? Let us know below...

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