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TIME 100's Health Stars: 3 Medical Minds Who Are Making A Difference

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TIME Magazine announced their 2012 TIME 100 list -- 100 honorees who were the biggest newsmakers and influencers of the year. Among them were three important health professionals that have been instrumental in effecting the kind of medical innovation that continues to keep us healthy.

Barbara Van Dahlen

Van Dahlen, a psychologist, founded the organization Give an Hour, which connects mental health care professionals with military personel who are suffering from post-traumatic stress disorder.

"Barbara has tenaciously attacked the epidemic of posttraumatic stress disorder, helping break through the stigma that prevents many from seeking help," wrote Admiral Mike Mullen in his short profile.

Ron Fouchier

A preeminent virologist, Fouchier is the man we want during a pandemic. His work on strategies to contain the H5N1 bird flu virus may lead to new ways we can prevent the spread of highly infectious disease.

"Fouchier’s work was designed to help scientists better understand how H5N1 could mutate and how to try to control it if it does," wrote Park.

Robert Grant

Grant is an HIV/AIDS researcher, based at University of California, San Francisco. His work has spanned more than a decade and focuses on infection prevention.

"Treating HIV is one thing, but preventing infections to begin with is the ultimate goal," wrote TIME's Alice Park. "Robert Grant brought us one step closer to that target by championing the idea that two powerful life-saving antiretroviral (ARV) drugs, tenofovir and emtricitabine, which are currently used to treat HIV after a person becomes infected, could also protect healthy individuals from ever acquiring the virus, as long as they took the medications before they engaged in high-risk behaviors."

The TIME 100 list has been published annually since 2004 and includes, each year, a selection of "Scientists & Thinkers."


10 'Embarrassing' Items In Your Desk

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It happens to most of us: Tampons or pads laying beside our computer or underwear falling out of gym bags at work. Your office desk is often your home away from home, yet some women are still embarrassed by everyday items.

If you've ever had your boss walk by and question your desk items, remember, you're probably more embarrassed than they are. Let's face it, our prescription pills, deodorant and tampons are nothing to be ashamed of. Being embarrassed by these items usually starts before you even bring them to work. How often do you double-bag your tampons at drug stores or make excuses about carrying your 'friend's' pills?

There is one housekeeping rule we do recommend, and that's ensuring your desk surfaces are squeaky clean. A clean desk can be a significant stress reducer, according to ITworld.com. "Studies have shown a reduction in the stress level of workers when their clean desktops promote paying attention to one thing at a time," according to the site.

What are you most embarrassed about on your desk? Let us know in the comments below, or at @HuffPostCaLiv.

Here are 10 items you're probably embarrassed by -- and why you shouldn't be:

Making Sex Green: Give Your Body The Eco-Friendly Treatment

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Sex is the most natural thing in the world -- but what about all those less-than-natural products you're using to have it?

Though it may seem quite minor, the condoms and sex toys being used and thrown out add to landfills, and many of the lubricants and products that we're using inside our bodies contain chemicals that, frankly, could hurt us down the road.

"The sex toy industry isn't regulated -- everything is sold as a 'novelty' product," explains Kim Sedgwick, co-owner of Toronto-based eco-friendly sexual and reproductive health shop Red Tent Sisters.

She notes that because of that, most sex toys are often made with phthalates, a class of plastics that has been banned from other products, thanks to its links to health concerns, including reproductive issues and cancer. It also means the toy is more porous, making it difficult to clean properly.

Sedgwick recommends sex toys made from silicone, a non-porous material that doesn't break down as easily, so that it's not necessary to throw them out after only a few months of use. Rechargeable batteries are also a greener option, and many companies have moved towards that model as of late.

SEE: Products that can make your sex life a bit more eco-friendly -- and possibly more fun too. Story continues below:

Lubricants, meanwhile, can contain a couple of potentially harmful ingredients, including parabens and glycerine. Parabens are used as preservatives in many cosmetics and products, and alarms have been raised over the past few years about their ability to mimic estrogen and consequent relation to diseases like breast cancer. While both Health Canada and the U.S. Food and Drug Administration have found reports inconclusive, large companies like Jamieson have gotten on board with paraben-free products -- exactly what you should be looking for in a personal lubricant, says Sedgwick. Glycerine can cause issues for women prone to yeast infections, as it's a form of sugar and can increase the bacteria.

Birth control is a bit trickier -- with overpopulation probably the planet's biggest issue, not getting pregnant could be the greenest behaviour possible. But contraception isn't particularly environmentally friendly: Though there are many options for the Pill, each is a form of hormone therapy, a decidedly unnatural option. There are vegan and biodegradable condoms available, but it takes a bit of research to find, and they often must be shipped.

One option, the intrauterine device (IUD), is advocated by environmentalists like Adria Vasil, who calls it "the greenest form of birth control next to abstinence." It is, however, somewhat invasive, and doesn't work as an option for everyone.

Sedgwick's suggestion is the Justisse Method, which is taught by her sister and co-owner Amy. It involves charting the menstrual cycle using temperature, cervical mucus and various other physical indicators for fertility, and having sex based on that. Rates of efficacy are as high as 99 per cent, but it requires some serious attention to detail -- though it's free and doesn't use any products, if it's not followed consistently, it could result in an unwanted pregnancy.

No matter which toy, lubricant or birth control you choose, Sedgwick stresses the importance of going into a store and trying it out in person, at least the first time. While the embarrassment factor may be higher than simply ordering online, people can have adverse reactions to ingredients and textures, and speaking with someone who knows everything that's out there can make a world of difference.

Add Sparkle To Your Crown Jewels With The Jubilee Vajazzle

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An online sex shop has caused controversy by unveiling a limited edition vajazzle in honour of the Queen's Jubilee.

Saucy website Lovehoney.co.uk wanted to celebrate Queen Elizabeth's 60th anniversary on the throne with a sexy souvenir.

So they launched the 'Majazzle' - a package where women can decorate their private parts by sticking on crystal decorations in the shape of a crown.


Proud to be British: celebrate the Queen's reign even when naked

The vajazzle became a nationwide sensation after beauty salon owner Amy Childs performed them on The Only Way is Essex.

Former TOWIE star Maria Fowler revealed she would be decorating herself in honour of Her Majesty.

Accessorise a jubilee vajazzle with a jubilee thong. Check out the strangest Jubilee souvenirs here.

Glamour girl Maria, 25, said: "It's a brilliant idea. We'll all be going on the razzle. What better way to dazzle than with your very own
Majazzle.

"It will be the jewel in the crown of the Queen's celebrations."

Neal Slateford, owner of Lovehoney, admitted he wanted to "get in on the fun".

He said: "It's in patriotic red white and blue and you can wear it anywhere - making it a jubilee for your jubblies or a sparkling street party for your sexy bits.

Last year the website produced a commemorative Royal Wedding Ring which allowed amorous couples to enjoy a special union of their own.

Source: SWNS

The Healthy Perks Of Having A Pup

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By Jessica Gross for YouBeauty

Picture it: You come home from a long day to your dog bounding toward you with the unbridled excitement equivalent to a celebrity spotting and giving you one big, wet lick on your cheek. It's hard to imagine a better instant mood-booster. But there are a myriad of other benefits to welcoming a furry friend into your fold, from increased self-esteem to more exercise and less loneliness.

Once you've decided to bring a dog into your home, find out how you can make the most out of your time with your pup -- and gain those health and beauty benefits to boot.

More from YouBeauty:
Health Benefits of Owning a Pet
The Beautiful Benefits of Touch
Six Tips for Getting Fit This Spring

Cuddle With Your Dog
Fido won't do you much good if he's always off in a corner by himself. Alan Beck, Ph.D., director of the Center for the Human-Animal Bond at Purdue University School of Veterinary Medicine and his co-researcher Aaron Katcher found in the early '80s that when people interact with dogs, "you actually get a drop in blood pressure -- a true relaxation response," he says. More recently, researchers in Japan found that dog owners who were bonded to their pets experienced a spike in oxytocin -- a neurotransmitter that helps us cope with stress -- from simply meeting their dogs' gazes.

We're social animals, so we gravitate toward this kind of bonding behavior: "Every culture has touch as a positive thing, because social animals have to be near each other," Beck says. Feeling a bit stressed? Try taking a few moments to pet or cuddle with your pup. He'll benefit from it, too.

Talk To Your Neighbors
A lot of the stigma against talking to strangers on the street disappears when you're walking with your dog. A study done in 2000 found that an experimenter walking a dog had three times as many social interactions than when she walked alone. That's because animals can serve as social facilitators, according to Beck. This isn't just a matter of small talk: What starts as a casual chat at the dog run can carry over into friendship or even a long-term relationship.

(On a personal note, since I got a dog six months ago, I've become friendly with a good majority of the people in my building. I live in New York City, and trust me, this isn't the type of place where neighbors become friends.) Once in a while, take out those iPhone earbuds and just stroll with your four-legged friend. You never know when that cute guy with the Husky will be walking down your block.

Play With Your Dog
"The greatest pleasure of a dog is that you may make a fool of yourself with him, and not only will he not scold you, but he will make a fool of himself, too," Samuel Butler, the novelist, once said. As we age, it's so easy to get caught up in our work and our daily list of "to do's" that we forget how to play. If you let him, your dog can be a portal into a more visceral, imaginative, emotional world -- and a less self-conscious one.

In a recent episode of NPR's Fresh Air, Jonah Lehrer points out that in fourth grade, kids start to become aware of the possibility of making mistakes, which can hugely limit their artistic creativity. "All of a sudden, they're aware that you can draw the wrong line, you can put the brush in the wrong place," he says. Being foolish with our dogs can -- momentarily and hopefully beyond -- push us out of this state of self-reproach.

"Playfulness is the mindset of a sense of joy and interacting in a healthy manner," says Aubrey Fine, a professor at California State Polytechnic University and an expert on the human-animal bond. "Having a dog in your life definitely provides you with an outlet to release that inner child, so to speak. How many of us have acted silly in front of our pets, and we wouldn't act that way in front of our friends?"

Playing with your dog also focuses your attention. "It keeps you in the moment," says Beck. "So when you're talking and playing with your dog, your mind is not free to worry. We intuitively try and do this anyway -- we listen to music, we sit in a coffee shop, we watch TV -- just to keep our minds focused on what's going on right now. But if that focus is nature or an animal, it's that much easier."

Walk Your Dog
Forget about relying heavily on potty pads. Getting out a few times a day with your dog can help you not only meet people, but also incorporate exercise into your daily routine. And you already know about the incredible benefits of exercise, from the emotional -- more confidence and lower stress levels -- to the physical, like a stronger heart, lower blood sugar, more restful sleep, lower cholesterol and better memory. "Even basic walking is one of the best exercises you can do, for general health and weight management," Beck says. "The dog is a great trigger for that, because I've never seen a dog that doesn't want to walk anymore." So slip on your sneakers, grab a leash and go.

Tune In To Your Dog
Dogs are very attuned to humans' moods, which makes them a good gauge of what we're feeling. They're "an emotional barometer," as Fine puts it. "Dogs have been domesticated for about 12,000 years," he says. "One of the things that research has shown is dogs have learned over these years, perhaps better than any other being, how to read our non-verbal behavior."

The trouble comes when we're too preoccupied to notice. If you tend toward destructive behaviors like binge eating, which often happens in a trance-like state, practice using your dog's reaction -- likely an anxious one that mirrors your own mood -- as a cue to pause and think. Why are you digging into that ice cream container with such ferocity? Your pup won't have the answer, but his presence is a good reminder to seek it yourself.

For more on pets, click here.

Walking Could Help Fight Depression

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Walking is effective in helping to decrease depressive symptoms, according to a new review of studies.

Research published in the journal Mental Health and Physical Activity shows that "walking has a statistically significant, large effect on the symptoms of depression in some populations."

The review showed that walking works as well as other kinds of exercise in helping lower depressive symptoms.

The review included eight studies, evaluating a total of 341 people, which all showed that walking is able to lessen symptoms of depression. But the researchers cautioned that the ways the studies were conducted -- like how long the people walked, at what pace, and how often -- were different from study to study, so more research is needed to find what is the most effective.

"The beauty of walking is that everybody does it," Adrian Taylor, a professor at the University of Exeter who studies depression, addiction and stress, told BBC News.

The Mayo Clinic explained that exercise may help fight depression by prompting the release of chemicals in the brain that are linked with feeling happy, and could also help to calm the body by raising body temperature. It could also help by serving as a distraction, boosting confidence and social interaction, and serving as a "substitute" for more unhealthy coping practices like drinking alcohol.

For more great health benefits of walking, click through the slideshow:

Sophie Raworth Hopes For A Better Marathon This Year..

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An eclectic mix of celebrities will take their place on the London Marathon start line today, with newsreaders and actors lining up alongside models and reality TV stars.

BBC presenter Sophie Raworth will hope to avoid a repeat of her performance last year, when she crashed into a barrier on the side of the road and blacked out after hitting the 23-mile mark.

The 43-year-old was given oxygen and cared for by a St John Ambulance crew for two hours.

"I thought I was at a pop concert at Leeds when I woke up. It was black and there was a lot of screaming.

"It honestly took me about 10 minutes to realise why I was there," she said.

The newsreader blamed the unusually high temperature of 19C (66.2F) for her collapse.

The cast of The Only Way Is Essex is strongly represented with James "Arg" Argent, Cara Kilbey and Billi Mucklow all competing.

Kilbey and Mucklow are running together and declared there was "no chance" they would finish behind Arg.

"We've got to beat him," Mucklow said.

She revealed that her experience of teaching yoga has helped with her breathing while pounding the streets, but admitted that "nothing prepares you for this run".

Other famous faces competing include celebrity chef Gordon Ramsay, who failed to complete the 2010 marathon owing to cramp, and ex-model Nell McAndrew, running her sixth marathon.

The former Playboy cover-girl is looking to break the three-hour mark for the first time today.

McAndrew's past times have been so quick that she has qualified to compete with the elite athletes.

"I am in the best shape, the fittest, I have ever been in my life," said the 2005 Rear of the Year winner.

Former Holby City actress Amanda Mealing will celebrate her 45th birthday at the race.

Mealing is running for the charity Breast Cancer Care after making a full recovery from the disease.

"I would get up on stage in front of thousands of people absolutely fine (but) I'm terrified of this.

"I think it's because it's so personal," she said.

Famous figures from the world of sport include England cricket coach Andy Flower, raising money for the Lord's Taverners, who took time out from the team's recent tour of Sri Lanka to train with a 15-mile run through rush-hour traffic in Galle.

James Cracknell, a double Olympic gold medal winner with the British rowing team, is aiming to continue his remarkable record of physical feats by running a third sub-three hour marathon.

The athlete, running for the Children's Trust, has also rowed the Atlantic, walked to the South Pole and recovered from a life-threatening head injury suffered while attempting to cycle, row, run and swim from Los Angeles to New York in under 16 days.

Clayton Blackmore, the former Manchester United full-back, is running for the Rhys Daniels Trust, whilst fellow ex-Wales international Matt Jones is running to raise money for the Spinal Injuries Association, the Bobby Robson Foundation, and the John Hartson Foundation.

Television stars include former I'm a Celebrity... contestant Linda Barker, presenter Isobel Lang, Coronation Street's Paula Lane, Bruno Langley, Conor Ryan and Nikki Sanderson, and Irish broadcaster Craig Doyle.

Alex Reid was forced to withdraw from the race after suffering an injury. A statement on the cage fighter's website revealed he had fallen down a flight of stairs and sprained his ankle.

Hair Dryers Sold At Costco Recalled Due To Potential Hazard: Health Canada

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OTTAWA - Health Canada has issued a recall for select hair dryers due to a potential defect found in the products.

The department says Testarossa TST65C Professional Hair Dryers sold at Costco stores across Canada are affected by the recall.

Health Canada says the cracking or failure of the screw boss on the dryers may result in small plastic or metal coming loose and potentially ejecting from the item during usage.

Around 57,000 units of the dryers were sold from July 2011 to March 2012.

The recall involves Testarossa professional hair dryers identified by model TST65C and UPC code 068459 060419.

The model number can be found near the certification label on the handle of the hair dryer. The date code can be found on the plug prong and those included in this recall are: 0511YL, 0611YL, 0711YL and 1111YL.

Neither product manufacturer Conair nor Health Canada has received any reports of incidents or injuries to Canadians related to the use of these dryers.

Take a look at what dangers are hiding in your daily beauty routines.


Burger Me! A Cheeseburger Crown Crust Pizza, For When Just Carbs And Dairy Aren't Enough

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Taking pizza to places it has never been before (and probably shouldn't go), Pizza Hut has unveiled its latest offering – namely a pie with a crust made of cheeseburgers.

Yes, the Cheese Burger Crown Crust Pizza is a hearty slab of cheese, regally surrounded by “grilled mini cheeseburgers nestled in golden crown crusts”.

The pizza, which comes with a beef topping as well as its loop of burgers, is on tables in Pizza Hut Middle East.

If you’re in the mood for something lighter, you can go for the ‘healthy’ option of the Chicken Fillet Crown Crust Pizza.

A mouthwatering menu blurb speaks of “chicken fillet balls nestled in golden crown crusts.”

It adds: “Then relish the rest of the pizza that’s topped with breaded chicken tenders, chicken strips, green peppers and laced with barbeque sauce.”

SEE ALSO

It comes a month after Pizza Hut UK launched the Pizza Dog, complete with a hotdog-filled crust.

Available only for home delivery, the Pizza Dog features: “Succulent hot dog sausage bursting from our famous stuffed crust, with a FREE mustard drizzle.”

A limited edition offer, the porky pie is apparently a nod to the world's first sausage-filled pizza, which made its debut in Japan in 2007.

7 Common And Annoying Skin Conditions

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By: Nicole Blades of Daily Glow

We’ve all heard it: Love the skin you’re in. Although this advice sounds simple enough, exasperating skin conditions like ingrown hairs, cellulite, and brown skin spots make it anything but easy for you to follow through. To get to the bottom of it all, we talked to dermatology experts about the most common (and annoying!) skin conditions and how to treat them.

Boost your skin confidence with these tips from top dermatologists on how to treat those annoying ingrown hairs, brown skin spots, cellulite, and more:

Milan Furniture Fair Focuses On Quality Pieces At Accessible Prices

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MILAN - Philippe Starck says his philosophy of democratic design, or quality pieces at accessible prices, is paying off in the ongoing economic crisis.

"People are intelligent. They want quality. They want a high level of creativity, but everyone will have less money," Starck said in an interview during the Milan Furniture Fair, which ended Sunday.

The times, he said, favour the kind of creative impulse that led to his decades-long collaboration with the Italian design company Kartell, which specializes in plastic contemporary furniture.

"This was my intuition 40 years ago when I started design," he said. "Now we have the reward of the political and philosophical choice."

Take a look at some of the pieces found at the fair. Story continues below.

In that mood, the mainstays of this year's Milan Furniture Fair, the industry's premier event, were not about costly redecorating.

Instead, designers showcased a few distinctive pieces that inspire and give new impulse to a room, as well as technological advances to make life easier.

Starck presented "Miss Less," a glossy plastic chair formed on a slim backrest atop a square base, as well as a pair of aluminum candlestick holders that when placed together appear to be lost in an embrace called "Abbraciaio," and light plastic document holders named "Archive." Something for everyone. The French designer, who has a home on one of Venice's islands, also lent his iconic "Mademoiselle" chair to design newcomer Lenny Kravitz, who clad the plastic chair in python, fur and leather.

Despite the persistent crisis, which has seen Italian furniture revenues contract by 5 per cent to $20 billion in 2011 from 2010, requests for space at the enormous Rho Fairgrounds outside Milan outstripped availability by 19,000 square meters (200,000 sq. feet), organizers said. The event attracted some 300,000 visitors with events that spill over into showrooms, museums and design spaces throughout the city, which gives the event a high-design street fair feel.

It is not just furniture-makers competing for attention of the design community.

The Tumi luggage and accessories brand chose the weeklong event to create a buzz around a new line of lightweight hard luggage designed by New York-based Israeli designer Dror Benshetrit, who spent 18 months making prototypes. The sleek Dror collection features angular cut surfaces, giving the pieces a modern esthetic that also employs an engineering trick to give added resistance.

London-based artist Jules Wright got the chance to test out the luggage on a five-country European tour filming a short film that looped at the collection's unveiling at Milan's Museum of Science and Technology.

"They were light, and we had them absolutely rammed," she said.

In a more traditional vein, Knoll premiered a new line of contemporary lounge furniture that it commissioned from French designers Pierre Beucler and Jean-Christophe Poggioli of Architecture & Associes, who brought an architect's sense of space to furniture design.

The pair created a cinematographic collection of sofas, armchairs and chaise lounges that maintain a comfortable softness within a disciplined line. The designers said they spent months testing the cushions to get the correct firmness for the seats and softness for the backrests.

While the new lounge collection has a classic feel, the pair also paid special attention to modernist touches — putting armrests on sofas that can comfortably accommodate today's paraphernalia: smart phones, tablet computers and remote controls. The pieces can easily be grouped in, say, an office lounge or waiting room, but can also stand alone — an esthetic and economic choice.

The Swiss kitchen appliance maker Franke rolled out its new smart phone-controlled oven, "My Menu," that speaks to today's hectic pace. Users can design menus in the smart phone app, which gives a shopping list and recipes to dinner party size. Then the courses can be put simultaneously into various levels of the oven, and cooked to order. The user is free to join guests for a chat and a cocktail, receiving a message on the phone as each course finishes cooking.

Franke also commissioned four architects to create concept kitchens.

Indian designer Satyendra Pakhale designed a compact kitchen in deep red and an abundance artificial light, recognizing that urbanites worldwide have limited space for cooking and cannot count on natural sunlight. In it, he put the full-sized "My Menu" oven, an island with a sink and a stove top — all in a 2.5 square meter (27 sq. feet) space.

"I wanted to kind of create a conception for a future kitchen, which will have a quality space and a very cheerful atmosphere," said Pakhale in a phone interview from the Netherlands. "I can't think of any culture where the kitchen is not important. It is primal."

A stroll through Milan during the fair revealed surprises at nearly every turn. At the Triennale design museum, acrobats performed amid design objects and percussionists filled the halls with dissonance, to the amusement of late-night design enthusiasts. An exhibit of miniaturized chairs from the Vitra Design Museum was on display at the Hugo Boss San Babila boutique, from Ludwig Mies van der Rohe's "Barcelona chair" to Marcel Breuer's "Wassily." And anyone with an iPhone could discover a virtual exhibit of impossible designs at five locations in Milan, including the piazza outside of La Scala.

There, artist Denis Santachiara planted his notion of a design project that would never be realized: personalized urns.

In Santachiara's vision, a client could order many small urns, creating small memorials with even personalized inscriptions to leave to loved ones on one's earthly departure. Concept urns, based on a model who happened to be an opera singer, were visible to passers-by with iPhones near Milan's La Scala opera house.

"It's like a souvenir of her life," Santachiara said. But the urns are nearly impossible to imagine commercially, hence their inclusion in "Design Impossible."

Santachiara's exploration is based on technology that allows designers to create personalized objects, mostly in plastic, from machines referred to as three-dimensional printers.

At the Rho fairgrounds, he showed a personalized foot stool he designed for Campeggi that bears the profile of the client, or someone of the client's wishes, based on a picture sent via Internet. The profile becomes the basis for an upholstered stool.

Santachiara also is pushing the envelope on the idea of transformational design, assigning students to come up with projects that involve transforming data from the Web into objects — conceptually "downloading" them from the Internet. In one case, students have proposed making furniture or accessories based on users' fingerprints, photographed from a webcam. In another, users would scan a child's drawings, which are then turned into toys or chocolates. And in yet another, the mathematical rendering of voice or music patterns can transform into design objects, like jewelry or lighting fixtures.

"We are transforming these into products," Santachiara said. "Something from our own molecules is transformed into computer bites and then into something more."

A Look At Cognitive Deficits From Cancer Chemotherapy

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By Scicurious
(Click here for the original article)

When we think about cancer, what we usually think about is a cure. Science has made great strides in treatments for cancer, such as chemotherapy, radiation, and surgery. Some cancers, such as breast cancer and childhood leukemia, have 90% survival rates, and survival is always a cause for celebration.

But with the success cancer treatments, questions arise after the celebration. What are the long-term effects of chemotherapy? How will someone’s quality of life be impacted after the cancer? These are important questions to ask. Chemotherapy has many side effects immediately after delivery; everyone knows about the nausea, vomiting, and headaches. But there are also consequences of chemotherapy in the long term, including cognitive dysfunction. Patients who have been treated with chemotherapy for leukemia as children suffer from increased medical complications, poor academic outcomes, and impairments in executive brain function such as working memory and attention. Adult women who have been treated with chemotherapy for breast cancer show problems with memory performance, which correlates with brain changes included decreased volume in areas like superior frontal gyrus and parahippocampal gyrus, important areas for learning and memory.

How do we go about trying to help people with this cognitive dysfunction? The usual “cognitive enhancers” like Ritalin may work, though they might have a larger side effect profile in some people who have undergone chemo, and Modafanil also shows promise. Erithropoetin works during chemotherapy, but what about later? But the real issue is not treatment, it’s know why people who undergo chemotherapy have long-term cognitive dysfunction. How does it occur? What does it mean?

If we are going to help the cognitive dysfunction that occurs after chemotherapy, we need to find ways to study it. There are many potential confounds. First, there are the confounds associated with cancer itself: fatigue, the effects of surgery, elevated cytokines and other inflammatory markers. Chemotherapy drugs are often given in batches, and the combinations are often changed. There are many things that could confound how much cognitive impairment cancer patients experience. In order to try and get around the many confounds associated with studying the cognitive effects of chemotherapy in humans, Ellen Walker and her group at Temple University are looking at the effects of chemotherapy drugs in mice, looking in particular at adults, and at juvenile mice treated with chemotherapy.

First, the group looked at adult female mice doing an operant task, putting their noses into a nosepoke hole to receive food. The animals learn the task on the first day, and are back into the test the second day, to see how well they recall what they learned.

Walker and her group found that chemotherapy drugs like paclitaxel, carboplatin, and 5-Fluorouracil disrupted the performance of the mice, and the effects were not dose dependent. In a dose-dependent response, the learning deficits would get worse as the dose increased, but in this case, the effects of learning were actually worse at lower doses of carboplatin, meaning that we can’t just lower the dose to try and prevent the effects of cognitive impairment.

Walker et al also wanted to look at the effects of chemotherapy in a childhood model. So they looked a young mice treated with the chemotherapy drugs mexthotrexate or cytarabine individually and in combination during development, carefully mimicking the doses used in humans. Then they tested the mice in a cognitive test called ‘novel object recognition’ when they were adults. Novel object is fairly simple, you give a mouse a single object on the first day, which it explores and gets to know. On the second day, you give it the first object, and a second, unknown object. This makes the mouse discriminate between an object it has seen before and one it hasn’t. Mice treated with methotrexate or cytarabine showed deficits in novel object discrimination, suggesting that being treated with chemotherapy drugs during development resulted in cognitive deficits, similar to those seen in humans.

And the changes went further than cognitive deficits. The mice treated with chemotherapy during development also showed more sensitivity to the rewarding properties of amphetamine (spending more time in drug paired environments).

By developing models of chemotherapy treatment in mice, Walker et al hope to understand the mechanisms that might underlie the cognitive dysfunctions seen in humans. Then, they hope to find ways to help, and help cancer survivors experience their new lease on life without some of the problems that might go with it.

'Hungary' Diabetics Who Break Diets Won't Receive Treatment

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Hungarian diabetics will be ‘punished’ if they fail to stick to their healthy eating diet by being banned from having modern treatment – a government decree has announced.

Under new rules, diabetics will have blood tests every three months and if their blood sugar levels are higher than average, officials will have the right to restrict the patients’ access to treatments using analog insulin (an expensive, more effective form of insulin).

The Hungarian government is hoping that this new scheme will reduce the amount of money spent on diabetes care – around 30 billion Hungarian forints (around £82m).

“Taxpayers’ money should not be spent on patients who don’t cooperate with their doctor,” states the decree, published in the Official Journal.

Will the UK follow suit?

In Britain, the cost of diabetes to the NHS is around £1m an hour, or 10% of the NHS’ budget for England and Wales. This equates to approximately £16,666 being spent on diabetes every minute.

In total, £9 billion is spent a year treating diabetes and the complications that follow.

It’s estimated that the cost of diabetes in the UK will soar to £4m an hour by 2025.


Can Anti-Depressant ‘Happy Pills’ Cure Osteoarthritis?

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A drug designed to beat depression could provide effective, life-changing treatment for osteoarthritis of the knee, researchers have found.

Depression drug 'duloxetine', which increases the levels of feel-good chemicals (such as serotonin and noradrenaline) in the nerves, has also been found to ease arthritis pain in knee joints, say researchers at University of Maryland.

The treatment, which costs £22 for a month’s supply, was given to a group of osteoarthritis sufferers for 13 weeks – and placebo pills given to another group of participants.

Patients who took the drug reported a 33% drop in pain levels compared to those who took the placebo medication.

These findings were published in the Journal of Rheumatology.

A spokeswoman for Arthritis Research UK said in a statement: "We know that the class of drugs to which duloxetine belongs have a propensity to modify chronic musculoskeletal pain; back pain in particular, but it’s not clear if it works well in peripheral joint osteoarthritis.

"There have been a number of trials of this drug that have shown mixed results.”

Antidepressants are used in a number of pain-relieving medications to help treat conditions such as migraines, pelvic pain and nerve damage.

According to the Mayo Clinic, the drug's pain-killing mechanism is still not fully understood.

However, previous studies have shown that arthritis pain is often worse in patients suffering from depression - and those using an anti-depressant may benefit from decreased sensations of pain.

According to Arthritis UK, people with long-term arthritis are two to three times (20%) more likely to experience depression. And around 68% of patients admit that their depression is worst when the pain levels are highest.

Emer O’Neill, spokesperson for the coalition and chief executive of Depression Alliance said in a statement: “You are twice as likely to experience depression if you have a long term condition.

“Depression is a debilitating condition and having a double whammy of a long-term condition and depression has an undoubtedly serious effect on a person’s quality of life and health.

“As a coalition of charities, we are calling for equal importance to be given to the physical and psychological symptoms of long-term conditions. We must start treating those with chronic conditions as a ‘whole person’ – and not just their physical condition”

Worldwide Measles Deaths Dropped Over A Decade: WHO

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LONDON — The number of measles deaths worldwide has apparently dropped by about three-quarters over a decade, according to a new study by the World Health Organization and others.

Most of the deaths were in India and Africa, where not enough children are being immunized.

Health officials estimate about 9.6 million children were saved from dying of measles from 2000 to 2010 after big vaccination campaigns were rolled out more than a decade ago. Researchers guessed the number of deaths fell during that time period from about 535,300 to 139,300, or about 74 percent.

But the figures come with a big grain of salt; scientists only had solid data for 65 countries. For the 128 others, they used modeling to come up with their estimates.

Despite the major dent, the progress fails to meet a WHO target to cut measles deaths by 90 percent by 2010.

"This is still a huge success," said Peter Strebel, a measles expert at WHO and one of the authors of the study. "You don't reduce measles deaths by three quarters without significantly accelerating efforts."

He noted that the global 85 percent vaccination coverage rate was the highest ever recorded.

The study was paid for by the U.S. Centers for Disease Control and Prevention and was published Tuesday in the journal, Lancet.

Measles is one of the most infectious diseases that exists and mostly affects children. It causes a fever, cough and a rash all over the body. The disease kills about one to two children for every 1,000 it infects and can also cause pregnant women to have a miscarriage or premature birth.

Past progress in reducing measles has led some health officials to consider whether they can eradicate it. Smallpox is the only human disease to have been wiped out. Other initiatives to rid the world of diseases including polio and guinea worm remain largely stalled.

"I am cautious about adopting too many eradication campaigns at once," said Nancy Leys Stepan, author of a book on disease eradication and a professor at Columbia University. She was not linked to the study.

Stepan said problems like getting good data and the challenges of eradication make it more reasonable to stick to deadlines for reducing measles rather than trying to eliminate it.

In recent years, the disease has surged in Europe – the number of people infected since 2007 has tripled. Doctors say measles cases are rebounding in Europe because people don't realize how serious the disease is and are skeptical of the vaccine.

The first measles shot was licensed in the U.S. in 1963 and is now widely included in routine childhood immunization programs in developed countries. Last year was the worst year for measles in the U.S. in 15 years, with 222 cases – mostly imported by foreign visitors or by U.S. residents infected overseas.

Daniel Berman, a vaccines expert at Medecins Sans Frontieres, noted there has been a massive increase in measles across Africa in the last two years, largely because of backsliding on immunization campaigns and declining funds.

"The challenge is to find ways to make measles campaigns happen in countries with weak systems," he said.

Berman said it would be hard to dramatically improve the 74 percent drop in measles deaths and that it would probably plateau.

WHO's Strebel said just maintaining the decline in measles still requires a major effort. He added experts are not ready to set any eradication deadlines.

"Let's wait until we get a bit closer to the top of the mountain before we say if we can get there," he said.

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Online:

http://www.lancet.com

http://www.who.int/topics/measles/en/


Scientists Clone Genetically-Modified Sheep That Contains 'Good' Fats

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By Tan Ee Lyn
HONG KONG (Reuters) - Chinese scientists have cloned a genetically modified sheep containing a "good" type of fat found naturally in nuts, seeds, fish and leafy greens that helps reduce the risk of heart attacks and cardiovascular disease.
"Peng Peng", which has a roundworm fat gene, weighed in at 5.74 kg when it was born on March 26 in a laboratory in China's far western region of Xinjiang.
"It's growing very well and is very healthy like a normal sheep," lead scientist Du Yutao at the Beijing Genomics Institute (BGI) in Shenzhen in southern China told Reuters.
Du and colleagues inserted the gene that is linked to the production of polyunsaturated fatty acids into a donor cell taken from the ear of a Chinese Merino sheep.
The cell was then inserted into an unfertilized egg and implanted into the womb of a surrogate sheep.
"The gene was originally from the C. elegans (roundworm) which has been shown (in previous studies) to increase unsaturated fatty acids which is very good for human health," Du said.
China, which has to feed 22 percent of the world's population but has only 7 percent of the world's arable land, has devoted plenty of resources in recent years to increasing domestic production of grains, meat and other food products.
But there are concerns about the safety of genetically modified foods and it will be some years before meat from such transgenic animals finds its way into Chinese food markets.
"The Chinese government encourages transgenic projects but we need to have better methods and results to prove that transgenic plants and animals are harmless and safe for consumption, that is crucial," Du said.
Apart from BGI, other collaborators in the project were the Institute of Genetics and Developmental Biology at the Chinese Academy of Sciences, and Shihezi University in Xinjiang.
The United States is a world leader in producing GM crops. Its Food and Drug Administration has already approved the sale of food from clones and their offspring, saying the products were indistinguishable from those of non-cloned animals.
U.S. biotech firm AquaBounty's patented genetically modified Atlantic salmon are widely billed as growing at double the speed and could be approved by U.S. regulators as early as this summer.
(Editing by Paul Tait)

Would You Buy Makeup For Your Toddler?

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Would you hesitate to buy makeup for your preteen daughter? What about your pre-preteen?

If you answered "yes" to either of those questions (the latter in particular), you'll likely sympathize with the women behind UK organization Pinkstinks. The Guardian reports that Pinkstinks founders Abi and Emma Moore are intent on stopping the marketing of makeup to very young girls.

On its website, Pinkstinks explains the rationale behind its new project:

Pinkstinks is committed to campaigning for a childhood free from pressure to conform, fit in and improve physical appearance. These pressures stem from corporate desire to create new markets whilst helping prepare young girls for lifelong commitment to the beauty industry; an industry which thrives on culivating self-doubt and body hatred.

The Pinkstinks website also enumerates the group's three specific demands: first, an end to the sale of makeup for girls under 8; second, an end to the giveaway of free makeup products with kids' items like comic books; and third, a resolution on the part of parents to "stop accepting and buying these products" for their kids.

Abi Moore spoke to the The Guardian about the proliferation of beauty-based toys for girls, lamenting that "[a]lthough there are still lots of home toys, girls' toys are now very much about being in front of a mirror: beauty parlours and leisure, makeup, brushing your hair, having a hairdryer aged two."

While Pinkstinks requests that makeup products be marketed to girls 8 and older, it's worth noting that tween-targeted makeup has also courted controversy in the past (the line of tween cosmetics launched last year by Walmart is a case in point).

In 2010, the New York Times reported on a NPD Group study about tween cosmetic use:

From 2007 to 2009, the percentage of girls ages 8 to 12 who regularly use mascara and eyeliner nearly doubled -- to 18 percent from 10 percent for mascara, and to 15 percent from 9 percent for eyeliner. The percentage of them using lipstick also rose, to 15 percent from 10 percent.

The marketing of makeup to young girls also plays into a larger -- often heated -- debate about the appropriateness of gender-specific toys and apparel for children. Earlier this year, a catalogue published by Swedish toy company Leklust made headlines for its purposeful contravention of traditional gender roles (it showed a girl riding a toy tractor and a young boy pushing a pram).

'Big Love' Actor Luke Askew Dies Of Lung Cancer At Age 80: How Is Age A Factor In Cancer?

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"Big Love" actor Luke Askew died from lung cancer last month in his home in Oregon, according to news reports.

The actor, who also acted in "Cool Hand Luke" and "Easy Rider," turned 80 three days before his death, OregonLive.com reported.

While there is little information on the circumstances of Askew's lung cancer -- what kind of cancer he had, how long he had it or what complications ultimately caused his death -- age is known to be a risk factor for many cancers.

According to the Cleveland Clinic, lung cancer is the No. 1 cause of cancer-related death for men when they are age 40 or older. For women, lung cancer outpaces breast cancer to be the leading cancer-related cause of death once they hit age 60.

Older people are more likely to develop lung cancer than young people, with 80 percent of lung cancers occurring in those ages 60 and older, according to MacMillan Cancer Support.

That's supported by a chart on the Centers for Disease Control and Prevention website that reveals an increase in lung cancer prevalence as we age. The chart, chart on its sitecalculates lung cancer risk based on current age. For example, 2.29 percent of men -- around two or three for every 100 men -- who are currently age 60 will go on to develop lung cancer in the next 10 years. However, that increases to 7.6 percent of men -- around seven or eight for every 100 men -- when looking ahead to the next 30 years.

But while age is a factor, the single greatest risk factor for lung cancer is smoking. The Mayo Clinic reports that lung cancer risk goes up the more cigarettes you smoke a day, and the more years you are a smoker (though quitting can mitigate your lung cancer risk).

Other risk factors for lung cancer include having a family history of the disease, being exposed to chemicals like asbestos or other cancer-causing materials, being exposed to radon gas, and being exposed to secondhand smoke, according to the Mayo Clinic.

Fire Starter Network (LIVE BLOG)

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Creative Geniuses tend to hang out with other Creative Geniuses and here at Healthy Living, our online community is a place to hang out and exchange our experiences. We’ll be cheering one another on, offering daily support and making this month an imaginative adventure to navigate together.

Each day, we’ll share your Facebook and blog comments in response to Danielle LaPorte’s "30 Days To Fire Up Your Creative Genius" challege (Missed it? You can still catch up HERE) through colorful word clouds that we hope serve as soul-firing inspiration.

If you haven’t, subscribe for the 30-Day challenge newsletter NOW. And don’t forget to share your answers with us here and on Twitter!


Every Plant In The World: Online Catalogue Of Plants Planned By Botanical Institutions

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ST. LOUIS - Four of the world's leading botanical institutions are working on a catalogue of every plant in the world, with plans to make the inventory of at least 400,000 species available for free online by 2020.

Those involved in the project say at least 100,000 plant species worldwide are threatened by extinction.

Plans for the catalogue called the World Flora were announced Monday by the St. Louis-based Missouri Botanical Garden, New York Botanical Garden and two British institutions, the Royal Botanic Garden Edinburgh and Royal Botanic Gardens, Kew.

The catalogue will include scientific information and images for every known species, with new ones added as they are discovered.

Officials at the botanical organizations say developing the catalogue is partly aimed at helping halt the loss of plant biodiversity around the world.

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