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Scientists have developed a new 'super aspirin' which has the power to treat 11 different types of cancer.
The Express reports that the new dug, known as NOSH, can be used in lower doses than conventional aspirin with fewer side effects, and tests have shown that it can shrink cancer cells by 85 per cent.
Research at the Sophie Davis School of Biomedical Education at The City College of New York has found that the drug is effective against cancers including colon, pancreatic, prostate, breast and leukaemia.
Previous research has shown that ordinary aspirin can reduce the size of some tumours by half, but prolonged use can have serious side effects, including bleeding, ulcers and kidney failure. However, the new formulation is much safer to take.
Professor Kashfi from the Sophie Davis School said: "If what we have seen in animals can be translated to humans it could be used in conjunction with other drugs to shrink tumours before chemotherapy or surgery."
He added: "The key components of this new compound are that it is very, very potent and yet it has minimal toxicity to normal cells.
"There'a s lot of data on aspirin showing that when taken on a regular basis, on average it reduces the risk of development of colon cancer by about 50 per cent compared to non-users.
Tests showed that just 24 hours after treating a culture of cancer cells, the NOSH aspirin had 100,000 times more potency than regular aspirin.
In a second study, mice with human colon cancer tumours were given NOSH aspirin. The drug caused cancer cells to self-destruct and reduced tumour growth, without any sign of toxicity.
Professor Kashfi said: "At 72 hours it is about 250,000 times more potent in an in-vitro cell culture against human colon cancer. So you need a lower amount to get the same result."
The
Daily Mail reports that the new compound is based on a hybrid of two previous formulations. One part of the hybrid aspirin releases nitric oxide (NO), which helps protect the stomach lining. The other releases hydrogen sulphide (H2S), which previous research has shown improves aspirin's cancer fighting ability.
Dr Kat Arney, science information manager at Cancer Research UK, told The Express: "Scientists have been investigating the cancer-fighting properties of aspirin for many year, although prolonged use can cause side effects such as stomach bleeds.
"It will be interesting to see how this particular compound progresses, although much more research is need to show whether it's safe and effective for use in humans."
Writing in the journal ACS Medicinal Chemistry Letters, Professor Kashfi said that treatment for humans was still years away, but toxicity testing and clinical trials would be the next step.
Professor Kashfi and his colleagues will present their findings at the annual meeting of the American Association for Cancer Research in Chicago at the end of the month.
How long do you think we'll have to wait before scientists can find a cure for cancer? Let us know below...
Click on the image below to find out how to reduce the risk of ovarian cancer...
- IVF
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Dutch researchers found that women who underwent IVF treatment <a href="http://lifestyle.aol.co.uk/2011/10/27/ivf-treatment-doubles-ovarian-cancer-risk/" target="_blank">almost doubled their risk for developing ovarian cancer</a>. Scientists believe IVF hormones are responsible for the increased risk.</p>
- Children and breastfeeding
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Studies have shown that women with children are at a lower risk for developing ovarian cancer than those who haven't given birth (risk is thought to reduce the more children you have). According to a Cancer Research UK study, breastfeeding for over six months can also help reduce your risk.</p>
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- Smoking
<p>
An analysis of multiple studies found that there is a link between smoking and ovarian cancer, with a doubling in ovarian cancer risk for mucinous ovarian tumours. However, the risk diminished some time after smokers quit.</p>
- Pain killers
<p>
While evidence is conflicting, a study published in 2006 found that pain killers like paracetamol and aspirin lowered the risk of developing ovarian cancer. A meta-analysis of data from multiple studies concluded that regular use of paracetamol reduced cancer risk by about one-third.</p>
- Talcum powder
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That lovely smelling talc could be giving you more than you bargained for. While research remains inconclusive, there is thought to be a link between talc use and an increased risk of ovarian cancer, due to potentially carcinogenic powder particles travelling through the female reproductive system.</p>
- Contraceptive pill
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A 2011 study found that women who took the birth control pill for a decade <a href="http://lifestyle.aol.co.uk/2011/10/26/how-taking-the-pill-cuts-the-risk-of-ovarian-cancer-by-nearly-ha/" target="_blank">nearly halved their risk of developing ovarian cancer</a>. It isn't a golden ticket, however - experts warned that breast cancer risk increased in women taking the pill. </p>
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